Some clinical applications of nanotechnology
1 Department of Medical Microbiology, Ahmadu Bello University, Zaria
2 Department of Textile Science and Technology, Ahmadu Bello University, Zaria
* Corresponding author: drfatimagiwa70@gmail.com
2 Department of Textile Science and Technology, Ahmadu Bello University, Zaria
* Corresponding author: drfatimagiwa70@gmail.com
Abstract
Nanomedicine can be succinctly defined as the application of nanotechnologies in a healthcare setting. Nanomedicine ascends from the integration of different sciences; physics, chemistry, biology, materials science, engineering, using the nanometer scale. This leads to scientists with different backgrounds, and diversified technical and intellectual skills, trying to address medical problems using nanotechnology. The task of nanomedicine is to integrate the knowledge of physicists, chemists and biologists to reach an ideal answer. Presently, nanomedicines are being explored for the management of various disease conditions which includes fungal infections, asthma and emphysema, ovarian and breast cancer, menopausal symptoms, chronic pain, kidney disease, multiple sclerosis. Nanotechnology is creating an insurrection, a paradigm shift in the manner we diagnose and treat disease. This treatise and current research concentrates on specific fields such as Nanodiagnostics, Molecular imaging, Dental Care, Orthopedics, Cardiac therapy and newly targeted drug-delivery systems. Nanomedicine offers hope for treatment of spinal cord injuries, diabetes, heart disease, Parkinson’s disease and cancer.
Keywords
Nanotechnology; Nanomedicine; Nanodiagnostic; Molecular imaging; Dental Care; Orthopedics; Cardiac Therapy; Drug delivery.
References
- Ariga T. (2006). Gene therapy for primary immunodeficiency diseases: recent progress and misgivings. Curr Pharm Des;12:549 - 56.
- Basavaraj KH (2012). 'Nanotechnology in medicine and relevance to dermatology: Present concepts'. Indian J Dermal, vol 57, pp 169-174
- Badve RR, Degwekar MD Martis EA (2012). 'Nanotechnology based devices and applications in medicine: An overview'. Chronicles of Young Scientists vol, 3, pp 68-73.
- Brigger I, Dubernet C, Couvreur P. (2002). Nanoparticles in cancer therapy and diagnosis. Adv Drug Deliv Rev;54:631 - 51.
- Cheng MM, Cuda G, Bunimovich YL, Gaspari M, Heath JR, Hill HD, (2006). Nanotechnologies for biomolecular detection and medical diagnostics. Curr Opin Chem Biol. 10:11 - 9.
- Freitas Jr RA. Nanodentistry. J Am Dent Assoc 2000;131:1559 - 65.
- Goracci G, Mori G. Micromorphological aspects of dentin. Minerva Stomatol 1995;44:377 - 87.
- Guccione S, Li KC, Bednarski MD. Vascular-targeted nanoparticles for molecular imaging and therapy. Methods Enzymol 2004;386:219 - 36.
- Hamon M, Lecluse E, Monassier JP, Grollier G, Potier JC. Pharmacological approaches to the prevention of restenosis after coronary angioplasty. Drugs Aging 1998;13:291 - 301.
- Hanakawa Y, Shirakata Y, Nagai H, Yahata Y, Tokumaru S, Yamasaki K, et al. Cre-loxP adenovirus-mediated foreign gene 30 expression in skin-equivalent keratinocytes. Br J Dermatol 2005; 152:1391 - 2.
- Hutcheson GD. The first nanochips. Sci Am 2004;290:76 - 83.
- Jain KK. Nanotechnology in clinical laboratory diagnostics. Clin Chim Acta 2005;358:37 - 54.
- Jain KK. The role of nanobiotechnology in drug discovery. Drug Discov Today 2005;10:1435 - 42.
- Kateb et al, 2011. Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: What should be the policy?' Neuro Image 54 pp.106-124
- Kayser O, Lemke A, Hernandez-Trejo N. The impact of nano- biotechnology on the development of new drug delivery systems. Curr Pharm Biotechnol 2005;6:3 - 5.
- Kong DF, Goldschmidt-Clermont PJ. Tiny solutions for giant cardiac problems. Trends Cardiovasc Med 2005;15:207 - 11.
- Koping-Hoggard M, Sanchez A, Alonso MJ. Nanoparticles as carriers for nasal vaccine delivery. Expert Rev Vaccines 2005;4: 185 - 96.
- Kubik T, Bogunia-Kubik K, Sugisaka M. Nanotechnology on duty in medical applications. Curr Pharm Biotechnol 2005;6:17 - 33.
- Labhasetwar V. Nanotechnology for drug and gene therapy: the importance of understanding molecular mechanisms of delivery. Curr Opin Biotechnol 2005;16:674 - 80.
- Li K.C, Pandit S.D, Guccione S, Guccione S, Bednarski MD. Molecular imaging applications in nanomedicine. Biomed Micro- devices 2004;6:113 - 6.
- Lin H, Datar RH. Medical applications of nanotechnology. Natl Med J India 2006;19:27 - 32.
- Mayer C. Nanocapsules as drug delivery systems. Int J Artif Organs 2005;28:1163 - 71.
- Mazzola L. Commercializing nanotechnology. Nat Biotechnol 2003; 21:1137 - 43.
- Medintz IL, Uyeda HT, Goldman ER, Matoussi H. Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 2005;4: 435 - 46.
- Misra,R. Acharya, S. and Sahoo, S.K., 2010. 'Cancer nanotechnology: application ofnanotechnology in cancer therapy ' Drug Discovery Today, Volume 15, pp.842-850
- Moghimi SM, Hunter AC, Murray JC. Nanomedicine: current status and future prospects. FASEB J 2005;19:311 - 30.
- Orive G, Hernandez RM, Rodriguez Gascon A, Dominguez-Gil A, Pedraz JL, et al. Drug delivery in biotechnology: present and future. Curr Opin Biotechnol 2003;14:659 - 64.
- Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev 2003;55: 329 - 47.
- Parveen S, Misra R, Sahoo S K, 2012,'Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging', Nanomedicine: Nanotechnology, Biology and Medicine, vol. 8, no.2, pp. 147-166
- Shaffer C. Nanomedicine transforms drug delivery. Drug Discov Today 2005;10:1581 - 2.
- Shellhart WC, Oesterle LJ. Uprighting molars without extrusion. J Am Dent Assoc 1999;130:381 - 5.
- Slavkin HC. Entering the era of molecular dentistry. J Am Dent Assoc 1999;130:413 - 7.
- Smith AM, Dave S, Nie S, True L, Gao X. Multicolor quantum dots for molecular diagnostics of cancer. Expert Rev Mol Diagn 2006;6: 231 - 44.
- Ure D, Harris J. Nanotechnology in dentistry: reduction to practice. Dent Update 2003;30:10 - 5.
- Vasir JK, Labhasetwar V. Targeted drug delivery in cancer therapy. Technol Cancer Res Treat 2005;4:363 - 74.
- Verma IM, Weitzman MD. Gene therapy: twenty-first century medicine. Annu Rev Biochem 2005;74:711 - 38.
- Webster TJ, Waid MC, McKenzie JL, Price RL, Ejiofor JU. Nanobiotechnology: carbon nanofibres as improved neural and orthopedic implants. Nanotechnology 2004;15:48 - 54.
- West JL, Halas NJ. Applications of nanotechnology to biotechnology commentary. Curr Opin Biotechnol 2000;11:215 - 7.
- Wickline SA, Neubauer AM, Winter P, Caruthers S, Lanza G. Applications of nanotechnology to atherosclerosis, thrombosis, and vascular biology. Arterioscler Thromb Vasc Biol 2006;26: 435 - 41.
- Yoshikawa T, Tsutsumi Y, Nakagawa S. Development of nano- medicine using intracellular DDS. Nippon Rinsho 2006;64:247 - 52.
How to Cite
J, G. F., & B, I. E. (2015). Some clinical applications of nanotechnology. Nigerian Journal of Materials Science and Engineering, 6(1), 95-102.
G. F. J, and I. E. B, "Some clinical applications of nanotechnology," Nigerian Journal of Materials Science and Engineering, vol. 6, no. 1, pp. 95-102, June 2015.